Molecular Partners starts Phase 1/2a trial of DLL3-targeting radiotherapy MP0712 in SCLC, neuroendocrine tumors

PUBT · 5d ago
Molecular Partners starts Phase 1/2a trial of DLL3-targeting radiotherapy MP0712 in SCLC, neuroendocrine tumors
- Molecular Partners flagged a U.S. Phase 1/2a study of DLL3-targeting radiotherapy MP0712, with patient dosing underway in the first cohort.
- Initial clinical data are expected in 2026, with trial-in-progress posters scheduled for ASCO on May 30 and SNMMI on June 2.
- Earlier first-patient imaging and dosimetry results were presented in January 2026, supporting continued clinical development of the program.
- The trial aims to establish safety and set a recommended Phase 2 dose in small cell lung cancer and other DLL3-expressing solid tumors.
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