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U.S. stocks were slightly lower, with the Dow Jones index falling around 0.1% on Wednesday.

Shares of Johnson & Johnson (NYSE:JNJ) rose sharply during Wednesday's session after the company raised its FY2025 earnings guidance.

Johnson & Johnson reported a second-quarter 2025 adjusted earnings of $2.77 per share, down 1.8% year over year, beating the consensus of $2.68. The pharmaceutical giant reported sales of $23.74 billion, up 5.8% year over year and beating the consensus of $22.85 billion.

Johnson & Johnson shares jumped 6.5% to $165.24 on Wednesday.

Here are some other big stocks recording gains in today’s session.

• Smart Digital Group Limited (NASDAQ:SDM) shares jumped 37.5% to $18.82.
• SharpLink Gaming, Inc. (NASDAQ:SBET) rose 25.8% to $36.44 amid continued strength after the company recently provided updates on its ETH holdings and staking protocols.
• Rigetti Computing, Inc. (NASDAQ:RGTI) gained 24.4% to $15.83 after the company unveiled the industry’s largest multi-chip quantum computer.
• Opendoor Technologies Inc. (NASDAQ:OPEN) rose 23.5% to $1.2850.
• SS Innovations International, Inc. (NASDAQ:SSII) climbed 22.7% to $6.54. SS Innovations International announced it has installed over 100 SSi mantra surgical robotic systems in seven countries.
• DeFi Development Corp. (NASDAQ:DFDV) rose 19.6% to $29.52.
• Bitmine Immersion Technologies, Inc. (NYSE:BMNR) gained 19.4% to $47.73 after a 13G filing showed Peter Thiel–linked FF Consumer Growth disclosed a 9.1% stake in the company as of July 8, 2025.
• Circle Internet Group (NYSE:CRCL) rose 14.7% to $224.09 following a legislative reversal in Washington. The rally ignited after President Donald Trump announced he had secured the necessary support to advance a pivotal stablecoin bill just one day after it was blocked in a procedural vote.
• Joby Aviation, Inc. (NYSE:JOBY) gained 13.3% to $15.81.
• Sify Technologies Limited (NASDAQ:SIFY) jumped 11.8% to $5.40. Sify Technologies named JPMorgan Chase Bank as successor depositary for ADR program, effective July 23.
• Unity Software Inc. (NYSE:U) gained 12% to $33.24 after Jefferies analyst Brent Thill raised the price target from $29 to $35 while maintaining a Buy rating.
• Summit Therapeutics Inc. (NASDAQ:SMMT) rose 10.6% to $26.95.
• Karman Holdings Inc. (NYSE:KRMN) shares climbed 9.7% to $53.01.
• Galaxy Digital (NASDAQ:GLXY) gained 9.6% to $22.87.
• Brighthouse Financial, Inc. (NASDAQ:BHF) rose 8.9% to $51.63 following a WSJ report suggesting Aquarian is nearing a deal for the company.
• Victory Capital Holdings, Inc. (NASDAQ:VCTR) gained 7.7% to $68.61.
• Symbotic Inc. (NASDAQ:SYM) rose 7% to $51.93 after Oppenheimer raised its price target on the stock from $35 to $54.
• Cipher Mining Inc. (NASDAQ:CIFR) rose 6.2% to $6.34.

Now Read This:

• Citigroup Analysts Boost Their Forecasts After Upbeat Earnings

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