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U.S. stocks were mixed, with the Dow Jones index falling around 200 points on Monday.

Shares of Vera Therapeutics, Inc. (NASDAQ:VERA) rose sharply during Monday's session after the company released ORIGIN Phase 3 trial data.

Participants treated with atacicept for immunoglobulin A nephropathy (IgAN) achieved a 46% reduction from baseline in proteinuria as measured by 24-hour urine protein-to-creatinine ratio (UPCR), with a statistically significant and clinically meaningful 42% reduction in UPCR compared to placebo (p<0.0001) at week 36.

Vera Therapeutics shares jumped 56.6% to $29.67 on Monday.

Here are some other big stocks recording gains in today’s session.

• Applied Digital Corporation (NASDAQ:APLD) surged 44.8% to $9.89 after the company announced a 250MW AI data center lease with CoreWeave.
• Kymera Therapeutics, Inc. (NASDAQ:KYMR) climbed 33.3% to $39.53 after the company announced clinical data for its Phase 1 Healthy volunteer study of KT-621.
• Blueprint Medicines Corporation (NASDAQ:BPMC) gained 26.2% to $127.93 after the company announced that Sanofi will acquire them for $9.5 billion.
• Cleveland-Cliffs Inc. (NYSE:CLF) gained 23.2% to $7.18 after Trump said he would double their tariffs to 50%.
• Century Aluminum Company (NASDAQ:CENX) rose 22% to $18.89 after Trump said he would double their tariffs to 50%.
• Liquidia Corporation (NASDAQ:LQDA) gained 18.2% to $17.64 after the company announced it began shipping its newly FDA-approved Yutrepia. Additionally, Needham raised its price target on the stock from $25 to $32.
• REGENXBIO Inc. (NASDAQ:RGNX) jumped 16.4% to $10.30.
• Tempus AI, Inc. (NASDAQ:TEM) gained 14.1% to $62.95 after the company introduced its fuses program for precision-based medicine and xM for advanced cancer treatment response monitoring.
• First Majestic Silver Corp. (NYSE:AG) rose 10.6% to $6.83.
• Steel Dynamics, Inc. (NASDAQ:STLD) surged 10.5% to $135.93. Shares of steel and aluminum stocks traded higher after Trump said he would double their tariffs to 50%.
• Hecla Mining Company (NYSE:HL) gained 10.4% to $5.67.
• Nucor Corporation (NYSE:NUE) gained 10% to $120.20. BMO Capital analyst Katja Jancic upgraded Nucor from Market Perform to Outperform and raised the price target from $140 to $145.
• ImmunityBio, Inc. (NASDAQ:IBRX) rose 6.2% to $2.8250. ImmunityBio received FDA expanded access authorization for the treatment of Lymphopenia with ANKTIVA in patients with solid tumors
• Eldorado Gold Corporation (NYSE:EGO) rose 6.1% to $21.32.

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