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Shares of Blueprint Medicines Corporation (NASDAQ:BPMC) rose sharply in today's pre-market trading.

Sanofi SA (NASDAQ:SNY) announced plans to acquire Blueprint Medicines for $9.5 billion.

Blueprint Medicines shares jumped 26.9% to $128.62 in the pre-market trading session.

Here are some other stocks moving in pre-market trading.

Gainers

• Lyra Therapeutics, Inc. (NASDAQ:LYRA) shares jumped 199% to $14.74 in pre-market trading after the company reported positive results from the ENLIGHTEN 2 Phase 3 trial of LYR-210 achieving statistically significant results for primary and key secondary endpoints in the treatment of Chronic Rhinosinusitis (CRS).
• InMed Pharmaceuticals Inc. (NASDAQ:INM) rose 93.2% to $4.81 in pre-market trading.
• Vera Therapeutics, Inc. (NASDAQ:VERA) surged 69% to $32.02 in pre-market trading after the company said Atacicept ORIGIN Phase 3 trial met primary endpoint of reduction in UPCR for IgAN treatment.
• Brand Engagement Network, Inc. (NASDAQ:BNAI) jumped 68.5% to $0.47 in pre-market trading after gaining 13% on Friday.
• Basel Medical Group Ltd (NASDAQ:BMGL) surged 51.4% to $9.20 in pre-market trading after jumping 485% on Friday.
• Black Spade Acquisition II Co (NASDAQ:BSII) gained 37.3% to $13.29 in pre-market trading after falling 5% on Friday.
• DigiAsia Corp. (NASDAQ:FAAS) climbed 27.7% to $1.6990 in pre-market trading after jumping 24% on Friday.
• Cleveland-Cliffs Inc. (NYSE:CLF) rose 25.6% to $7.32 in pre-market trading.
• BioNTech SE (NASDAQ:BNTX) gained 14.1% to $109.32 in pre-market trading. BioNTech and Bristol Myers Squibb announced a global strategic partnership to co-develop and co-commercialize next-generation bispecific antibody candidate BNT327 broadly for multiple solid tumor types

Losers

• ReShape Lifesciences Inc. (NASDAQ:RSLS) shares dipped 23.2% to $3.77 in pre-market trading. ReShape Lifesciences entered into equity distribution agreement relating to sale of up to $9.7 million of shares of common stock.
• China Liberal Education Holdings Limited (NASDAQ:CLEU) shares fell 22.6% to $0.7500 in pre-market trading after the company announced suspension of Nasdaq trading.
• Silexion Therapeutics Corp (NASDAQ:SLXN) fell 20.2% to $0.8300 in pre-market trading after gaining 8% on Friday.
• SharpLink Gaming, Inc. (NASDAQ:SBET) declined 18.4% to $62.60 in pre-market trading after the company filed for mixed shelf offering.
• ContextLogic Inc. (NASDAQ:LOGC) shares tumbled 18.3% to $6.70 in pre-market trading. ContextLogic will commence trading on the OTC Markets and delist from the Nasdaq.
• Xilio Therapeutics, Inc. (NASDAQ:XLO) fell 17.9% to $0.8788 in pre-market trading after the company announced a proposed public offering.
• Super League Enterprise, Inc. (NASDAQ:SLE) fell 16.4% to $0.1629 in today's pre-market trading. Super League Enterprise, on Friday, announced a registered direct offering.
• Tian Ruixiang Holdings Ltd (NASDAQ:TIRX) dipped 16% to $1.68 in pre-market trading. TIAN RUIXIANG shares gained 8% on Friday after the company announced plans to buy Ucare for $150 million in an all-stock deal.
• Lucid Diagnostics Inc. (NASDAQ:LUCD) shares fell 15.1% to $1.18 in pre-market trading. Lucid Diagnostics may offer sell shares of common stock of up to $25 MILLION.
• Algoma Steel Group Inc. (NASDAQ:ASTL) fell 9.2% to $4.78 in pre-market trading.

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